Python is a general-purpose programming language, while MATLAB is focused on scientific computing and data analysis. Python can thus be used for a wider range of applications.

Python interfaces better with other programming languages like C, C++, Java, etc. It's thus more suitable for developing large complex projects.

Python allows building full-featured applications with GUIs, websites, etc. MATLAB is more limited for developing such applications.

Python can be used for web back-end development with frameworks like Django and Flask. MATLAB is not suited for web development. of course, MATLAB still retains some advantages over Python in areas like signal processing, machine learning, etc. But overall, Python is considered more flexible, easy to use, and suited for a wider range of applications.